How much does tissue pathology exam (biopsy), level IV cost in San Francisco, CA?

CPT 88305 — the fair price, every hospital's price, and the Medicare benchmark for San Francisco, CA.

Estimates only. Educational estimates from public Medicare benchmarks and hospital-published prices — not a guarantee, and not legal, medical, or financial advice.
88305 Tissue pathology exam (biopsy), level IV
Ask to pay
$107
About 2.0× what Medicare pays — most hospitals accept a self-pay rate in this range.
What Medicare paysⓘ
$53
Typical price near you
$249
Cash / self-pay price
$320
Prices near you — 19 facilities, lowest first
FacilityTypePricevs MedicareQuality
Dignity Sequoia Hospital (Redwood City) lowest Hospital $37cash 0.7× ★★★★★
Sutter Santa Rosa Regional Hospital (Santa Rosa) Hospital $78cash 1.5× —
Sutter CPMC Van Ness Campus (San Francisco) Hospital $130cash 2.4× —
Sutter Alta Bates Summit Medical Center (Oakland) Hospital $130cash 2.4× —
Sutter Mills-Peninsula Medical Center (Burlingame) Hospital $130cash 2.4× ★★★★★
Sutter Eden Medical Center (Castro Valley) Hospital $166cash 3.1× —
Dignity Dominican Hospital (Santa Cruz) Hospital $176cash 3.3× —
Kaiser Permanente San Francisco Medical Center (San Francisco) Hospital $230cash 4.3× ★★★★★
UCSF Medical Center (San Francisco) Hospital $249cash 4.7× ★★★★★
Natividad Medical Center (Salinas) Hospital $320cash 6.0× —
Providence Santa Rosa Memorial Hospital (Santa Rosa) Hospital $339cash 6.3× —
Stanford Health Care Tri-Valley (Pleasanton) Hospital $341cash 6.4× —
Prices from each hospital's public machine-readable file; imaging & surgery-center prices are published self-pay rates (often the cheapest option). vs Medicare is how many times the Medicare rate each facility charges. 2 unusually low/high prices excluded from the typical price as likely data errors.
💬 What to say — negotiation scripts
  • For 88305 (Tissue pathology exam (biopsy), level IV), Medicare's benchmark rate is $53.43. A fair self-pay target for this line is $106.86. If I was charged more than that, please reduce it toward this benchmark.
  • Your own published cash / self-pay price for 88305 is $320.00, and negotiated rates at nearby facilities run $130.00–$523.81. Please apply a rate in that range to my bill rather than the gross charge.
  • Please send a fully itemized bill listing every CPT/HCPCS/DRG code and its individual charge, so I can review each line against published rates.
  • Separately, what is your financial assistance / charity care policy, and am I eligible? Please send me the application and the income thresholds.
See tissue pathology exam (biopsy), level IV prices in another area

What should 88305 cost in San Francisco, CA?

For tissue pathology exam (biopsy), level IV (CPT 88305) in San Francisco, CA, a fair self-pay price is around $249, with hospitals ranging from $130 to $524 across 19 facilities. Medicare's benchmark rate is $53, the floor to negotiate toward. The card above lists each hospital's price, cheapest first, with CMS quality stars.

Frequently asked questions

How much does tissue pathology exam (biopsy), level IV cost in San Francisco, CA?

A fair self-pay price for tissue pathology exam (biopsy), level IV (CPT 88305) in San Francisco, CA is around $249, with hospital prices ranging from $130 to $524 across 19 facilities. These are estimates from hospital-published prices, not a guarantee.

What is the Medicare rate for CPT 88305?

Medicare pays about $53 for tissue pathology exam (biopsy), level IV (CPT 88305). That's the negotiation floor — a fair cash-pay target is roughly 1.5–2× it, well below typical gross charges.

Can I negotiate the price of tissue pathology exam (biopsy), level IV?

Yes. Under the federal Hospital Price Transparency rule hospitals must publish these rates, so you can ask to pay the cash or negotiated rate instead of the gross charge. Paste your bill on the home page for a ready-to-send appeal letter and the exact numbers to cite.

Got a bill for this?

If you were charged more than the fair price, you can usually negotiate it down. Paste your itemized bill to get a personalized appeal letter, the exact numbers to cite, an AI negotiation coach, and a charity-care eligibility check — free.

Compare other procedures in San Francisco, CA

Prices last refreshed September 2026 from each hospital's official CMS machine-readable file. Medicare rate: CY2025 OPPS/PFS/CLFS. Estimates only — not a guarantee.